Detecting High-Grade Cervical Disease on ASC-H Cytology

Atypical squamous cells: ASCUS is out! Now, ASC-US and ASC-H for reporting of cervical cytology.

ASC statement on new technologies in cervical cytology screening (June 2000). American Society of Cytopathology.

Relative Accuracy of Cervical and Anal Cytology for Detection of High Grade Lesions by Colposcope Guided Biopsy: A Cut-Point Meta-Analytic Comparison

BACKGROUND We recently reported, using a receiver operating characteristic area metric, the first meta-analytic comparison of the relative accuracy of cervical and anal cytology in detecting moderate or severe histopathologic lesions by magnification directed punch biopsy. The aim of the present research was to meta-analytically examine cut-point specific operating characteristics (sensitivity,...

Cytology and Human Papillomavirus Co-Test Results Preceding Incident High-Grade Cervical Intraepithelial Neoplasia

OBJECTIVE High-risk HPV (hrHPV) and cytology co-testing is utilized for primary cervical cancer screening and for enhanced follow-up of women who are hrHPV-positive, cytology negative. However, data are lacking on the utility of this method to detect pre-cancer or cancer in community-based clinical practice. This study describes cytology and hrHPV results preceding high-grade cervical intraepit...

Management of Women with High-Grade Squamous Intraepithelial Lesion and Atypical Glandular Cell Cervical Cytology

The management of women with high-grade squamous intraepithelial lesion (HSIL) and atypical glandular cells (AGC) cytological results is less controversial than the management of women with lower grade cytological abnormalities. In large part, this stems from the fact that women with both of these cytological results have a considerable risk of harboring a high-grade cervical intraepithelial ne...